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Delta 9-THCPosted at 4:51 PM on 11/7/2008
Since oral 9-THC has some analgesic activity, it is highly likely that smoked marijuana has some analgesic activity in some kinds of clinical pain. Because 9-THC from smoked marijuana is absorbed directly into the pulmonary circulation, this route of administration results in a 9-THC blood level curve much more like that produced by an intravenous injection than that after oral administration cannabis seeds. It is therefore likely that smoked marijuana potentially allows a more precise titration to effect than oral administration of 9-THC with its delayed, poor, and erratic bioavailability.
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